Enzyme Indicators (EI’s) have been proven as a revolutionary viable alternative to biological indicators (BI’s) for Hydrogen Peroxide decontamination validation. A white paper published by the Parenteral Drug Association (PDA) Journal of Pharmaceutical Science & Technology, and written by Public Health England (PHE), states that Enzyme Indicators are a “potentially valuable tool for rapid VPHP bio-decontamination cycle development and subsequent re-qualification.”

The paper entitled “Evaluation of novel process indicators for rapid monitoring of hydrogen peroxide decontamination processes” explains the process of comparing Enzyme Indicator performance against the current industry standard approach of using biological indicators (BI’s). Given ongoing concerns about the reliability and response time of BI’s, PHE explored the potential for an enzyme-based approach decontamination process evaluation.

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